Venture capital engineered to ignite your growth

With AI at our core, we're built like a tech company and dedicated to powering your next phase with data, unmatched portfolio support, and deep sector expertise.

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See how far our founders go

Discover what's possible when you're supported with AI, data, advisory programs, and sector experts.

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"From data science to hiring, SignalFire has added tremendous value above and beyond customer intros or fundraising advice."*

Jake Cooper

"SignalFire takes a product-oriented approach to what early-stage teams need, and built the product and founder experience around it."*

Anh-Tho Chuong

“SignalFire has been the most helpful investor we've had on our cap table thus far.”*

Rami Karabibar

Key Investment Sectors

Health & PharmaTech
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Enterprise
SaaS
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Cybersecurity
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Fintech
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Consumer
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Applied AI/ML & Vertical SaaS
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AI/ML Infrastructure & Tooling
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Enterprise Infrastructure & Developer Tools
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Our Sectors

Healthtech
Cybersecurity
Enterprise SaaS
Fintech
Consumer
Applied AI / ML + Vertical SaaS
AI/ML Infrastructure & Tooling
Enterprise Infrastructure & Developer Tools

The VC firm built like a tech company

We interviewed 500 founders to understand their needs, transformed portfolio support with AI—and founded a whole new VC model. Get to know our story and how we’ve scaled to over $2.1B in assets under management.
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Unbeatable support, from AI to Z

When you work with SignalFire, you get the best of AI and technology paired with unparalleled portfolio support.

In-house AI/ML Tools

Access to our elite talent search engine, competitive intelligence, and sales lead data all in one.  We built our Beacon AI Platform to meet your strategic needs.
Learn about Beacon AI

Portfolio Success as a Service

Level up with expert support and scalable programs for go-to-market, leadership development, recruiting, data science, PR, and fundraising.
See how we help

Deep sector expertise

Get the insights and guidance you actually need from seasoned experts in your industry.
See our sectors
Matt Loper
Matt Loper
CEO
“Every venture fund I’ve ever met has promised to add value beyond capital, but SignalFire is the first I’ve known to exceed all expectations.”*

Beacon AI platform

Our proprietary AI tools track the world's talent and the key go-to-market insights so you can hire and grow smarter.
More about Beacon

By the numbers

Support so meticulous, you can measure it.

85

NPS from our portfolio founders



650m

number of employees tracked by Beacon AI Platform


47

average number of support interactions a company has with SignalFire team per quarter

100%

companies that participate in at least one SignalFire program within 6 months of joining

You don’t just get one of us

You get all of us: a group of engineers, data scientists, product and growth professionals, expert mentors, and dedicated advisors focused on your success.
Meet the team

The latest

Explore our latest investments and news.
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SignalFire’s big bet on Qualified Health: Transforming healthcare with responsible AI
Portfolio
SignalFire
Investment
January 8, 2025

SignalFire’s big bet on Qualified Health: Transforming healthcare with responsible AI

Qualified Health is redefining AI adoption in healthcare by prioritizing safety, governance, and scalability. SignalFire is proud to lead Qualified Health’s $30M seed round, partnering with a visionary team tackling some of the biggest hurdles in AI adoption.
Read more
Fierce and SignalFire's Healthtech 20: The most-funded startups transforming healthcare
Beacon AI
Must-Read
December 19, 2024

Fierce and SignalFire's Healthtech 20: The most-funded startups transforming healthcare

Discover the top 20 most-funded healthcare startups and the biggest recent funding rounds in SignalFire’s latest report with Fierce Healthcare. Explore emerging trends like telehealth pharmacies, value-based care models, and lessons from flameouts like Olive and Forward Health.
Read more
From A to GenZ: How to build a multi-generational company
Advice
December 9, 2024

From A to GenZ: How to build a multi-generational company

Learn how startups can harness generational diversity to build stronger teams, adapt to shifting trends, and drive innovation. Get actionable tips for hiring talent from Gen X to Gen Z to Millennials and Baby Boomers.
Read more

*Portfolio company founders listed above have not received any compensation for this feedback and may or may not have invested in a SignalFire fund. These founders may or may not serve as Affiliate Advisors, Retained Advisors, or consultants to provide their expertise on a formal or ad hoc basis. They are not employed by SignalFire and do not provide investment advisory services to clients on behalf of SignalFire. Please refer to our disclosures page for additional disclosures.